Saliva is more effective in relieving the mother of morphine. - SimPle SCienCe

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Wednesday, January 31, 2018

Saliva is more effective in relieving the mother of morphine.

Saliva
SaliVa
In 2006, a substance stronger than morphine was discovered up to six times of morphine. And when tested on rats by saliva produced naturally within a human body.
  •  Natural painkillers are very rare in nature, and researchers and scientists hope that this modern discovery may be leaked to pathological treatments within global hospitals.
  • Naturally produced analgesics without any chemical intervention may contribute to overcoming some of the side effects that may be suspected of patients who have been treated by chemically produced compounds, especially morphine.
  • The compound was named Opiorphin, where Catherine Rougeot and her colleagues at the Pasteur Institute in Paris, France, announced the discovery at the National Academy of Sciences that it was extending the body's defense of pain by preventing the breakdown of the so- Enkephalins, which in turn activates opioid receptors that prevent pain signals from reaching the nerve center or brain.

    Morphine
    MorPhine
  • Rougeot also tracked the new compound after its discovery of a similar natural habitat in the rats called sialorphin2. So they asked several questions about the human body's ability to produce something like that - and during the analysis of saliva samples, they found Opiorphin.
  • Alistair Corbett, an opiate specialist at the University of Glasgow, Caledonian, UK, says it is the first natural substance to be found in humans that trigger pain relief. But it is unlikely that so-called polypeptide plays a major role in the pain relief process in the body; it can play a more important role, which is to protect the body and general chemicals from decomposition.
  • And to look more closely at this subject
  • Opiorphin appears to work on the pain caused by both chemical and physical means. When mice were injected in a painful manner, weak responses to pain, such as licking when injected with a claw, appeared. It also greatly contributed to pain relief when mice walked through the surfaces covered with a pin.
  • The researchers have tried several attempts in the past to make these synthetic compounds to do the same job to maintain Enkephalins, but without any results achieved.
  • But Sandy McKnight, former associate director of the Parke-Davis Research Center for Neurosciences in Cambridge, UK, issued a note warning: "The research was very comprehensive and despite all these efforts, such drugs may be reached after many trials the operation. And that it is unlikely that the prescription (uburephine) will be a good catalyst for the chemists to continue their efforts in this area. "
  • A substance such as (uburephine) may be sufficient to protect the Enkephalins from decomposition alone. This is worrying that the latter may have unexpected side effects.

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